Between brackets is the number of accepted species

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- Mollusca (132 791)
- Subphylum Aculifera
- Subphylum Conchifera
- Subphylum Placophora accepted as Polyplacophora
- Superclass Aplacophora
- Class Amphineura accepted as Aculifera
- Class Bivalvia (25 009)
- Subclass Autobranchia (23 295)
- Infraclass Heteroconchia (16 637)
- Subterclass Archiheterodonta (1 208)
- Subterclass Euheterodonta (11 356)
- Subterclass Heterodonta
- Subterclass Palaeoheterodonta (4 072)
- Order Trigoniida (1 482)
- Order Unionida (2 579)
- Superfamily Deccanoidoidea N. H. Shah & Patel, 2024 †
- Superfamily Etherioidea Deshayes, 1832 (148)
- Family Acostaeidae J. P. E. Morrison, 1973 accepted as Mulleriidae Deshayes, 1832
- Family Etheriidae Deshayes, 1832 (3)
- Family Iridinidae Swainson, 1840 (68)
- Subfamily Aspathariinae Modell, 1942 (25)
- Subfamily Dentaspathariinae Modell, 1964 † accepted as Coelaturini Modell, 1942
- Subfamily Iridininae Swainson, 1840 (27)
- Genus Dentaspatharia Modell, 1964 † (1)
- Genus Iridina Lamarck, 1819 accepted as Mutela Scopoli, 1777 (11)
- Genus Itaimbea [sic] † accepted as Itaimbeia Mezzalira, 1974 †
- Genus Itaimbeia Mezzalira, 1974 † (1)
- Genus Leptospatha Rochebrune & Germain, 1904 accepted as Chambardia Bourguignat, 1891
- Genus Pseudodiplodon W. Adam, 1957 † (2)
- Genus Pteromutela Starobogatov, 1970 accepted as Mutela Scopoli, 1777
- Genus Spatha I. Lea, 1838 accepted as Mutela Scopoli, 1777
- Subgenus Spatha (Aspatharia) Bourguignat, 1885 accepted as Aspatharia Bourguignat, 1885
- Subgenus Spatha (Leptospatha) Rochebrune & Germain, 1904 accepted as Chambardia Bourguignat, 1891
- Subgenus Spatha (Mutela) Scopoli, 1777 accepted as Mutela Scopoli, 1777
- Subgenus Spatha (Spatha) I. Lea, 1838 accepted as Mutela Scopoli, 1777
- Subgenus Spatha (Spathella) Bourguignat, 1885 accepted as Chambardia Bourguignat, 1891
- Species Spatha aequilatera E. von Martens, 1889 accepted as Chambardia bourguignati (Bourguignat, 1886)
- Species Spatha alata I. Lea, 1864 accepted as Mutela alata (I. Lea, 1864)
- Species Spatha anceyi Ancey, 1894 accepted as Chambardia wahlbergi (Krauss, 1848)
- Species Spatha approximans Preston, 1910 accepted as Chambardia nyassaensis (I. Lea, 1864)
- Species Spatha baikii H. Adams, 1867 accepted as Chambardia rubens (Lamarck, 1819)
- Species Spatha bellamyi Jousseaume, 1886 accepted as Chambardia wissmanni (E. von Martens, 1883)
- Species Spatha bertilloniana Preston, 1910 accepted as Chambardia wahlbergi (Krauss, 1848)
- Species Spatha bourguignati Bourguignat, 1886 accepted as Chambardia bourguignati (Bourguignat, 1886)
- Species Spatha caillaudi E. von Martens, 1866 accepted as Spatha cailliaudi E. von Martens, 1866
- Species Spatha cailliaudi E. von Martens, 1866 accepted as Chambardia rubens (Lamarck, 1819)
- Species Spatha compressa E. von Martens, 1860 accepted as Pilsbryoconcha exilis (I. Lea, 1838)
- Species Spatha corneola Rochebrune, 1886 accepted as Aspatharia ganciniensis (Rochebrune, 1886)
- Species Spatha corrugata Dautzenberg, 1893 accepted as Aspatharia rugifera (Dunker, 1858)
- Species Spatha cryptoradiata Putzeys, 1899 accepted as Aspatharia pfeifferiana (Bernardi, 1860)
- Species Spatha divaricata E. von Martens, 1897 accepted as Aspatharia divaricata (E. von Martens, 1897)
- Species Spatha droueti Chaper, 1885 accepted as Aspatharia droueti (Chaper, 1885)
- Species Spatha ganciniensis Rochebrune, 1886 accepted as Aspatharia ganciniensis (Rochebrune, 1886)
- Species Spatha hartmanni E. von Martens, 1866 accepted as Chambardia wahlbergi (Krauss, 1848)
- Species Spatha innesi Pallary, 1902 accepted as Aspatharia chaiziana (Rang, 1835)
- Species Spatha kamerunensis B. Walker, 1910 accepted as Aspatharia rugifera (Dunker, 1858)
- Species Spatha kirki (Ancey, 1894) accepted as Chambardia nyassaensis (I. Lea, 1864)
- Variety Spatha kirki var. liederi E. von Martens, 1897 accepted as Chambardia nyassaensis (I. Lea, 1864)
- Species Spatha lepsii Jickeli, 1874 accepted as Chambardia rubens (Lamarck, 1819)
- Species Spatha mabillei Jousseaume, 1886 accepted as Aspatharia pangallensis (Rochebrune, 1882)
- Species Spatha maitenguensis Sturany, 1898 accepted as Chambardia wahlbergi (Krauss, 1848)
- Species Spatha marnoi Jickeli, 1874 accepted as Aspatharia marnoi (Jickeli, 1874)
- Species Spatha modesta I. Lea, 1864 accepted as Chambardia petersi (E. von Martens, 1860)
- Species Spatha mwayana Preston, 1913 accepted as Chambardia nyassaensis (I. Lea, 1864)
- Species Spatha nyassaensis I. Lea, 1864 accepted as Chambardia nyassaensis (I. Lea, 1864)
- Species Spatha oppicata Germain, 1913 accepted as Chambardia wissmanni (E. von Martens, 1883)
- Species Spatha pangallensis Rochebrune, 1882 accepted as Aspatharia pangallensis (Rochebrune, 1882)
- Species Spatha petersi E. von Martens, 1860 accepted as Chambardia petersi (E. von Martens, 1860)
- Species Spatha renei Jousseaume, 1886 accepted as Chambardia rubens (Lamarck, 1819)
- Species Spatha rochebrunei Jousseaume, 1886 accepted as Aspatharia rochebrunei (Jousseaume, 1886)
- Species Spatha rotundata E. von Martens, 1897 accepted as Chambardia bourguignati (Bourguignat, 1886)
- Species Spatha rubens (Lamarck, 1819) accepted as Chambardia rubens (Lamarck, 1819)
- Species Spatha semicorrugata Preston, 1909 accepted as Aspatharia ganciniensis (Rochebrune, 1886)
- Species Spatha sinuata E. von Martens, 1883 accepted as Aspatharia sinuata (E. von Martens, 1883)
- Species Spatha stuhlmanni E. von Martens, 1897 accepted as Aspatharia pfeifferiana (Bernardi, 1860)
- Species Spatha tanganyicensis E. A. Smith, 1880 accepted as Pseudospatha tanganyicensis (E. A. Smith, 1880)
- Species Spatha trapezia E. von Martens, 1897 accepted as Chambardia trapezia (E. von Martens, 1897)
- Species Spatha tristis Jousseaume, 1886 accepted as Aspatharia rochebrunei (Jousseaume, 1886)
- Species Spatha wahlbergi (Krauss, 1848) accepted as Chambardia wahlbergi (Krauss, 1848)
- Species Spatha wissmanni E. von Martens, 1883 accepted as Chambardia wissmanni (E. von Martens, 1883)
- Genus Spathella Bourguignat, 1885 accepted as Chambardia Bourguignat, 1891
- Genus Taxodontites Simone & Mezzalira, 1997 † (1)
- Family Mulleriidae Deshayes, 1832 accepted as Mycetopodidae J. E. Gray, 1840
- Family Mutelidae Gray, 1847 accepted as Iridinidae Swainson, 1840
- Family Mycetopodidae J. E. Gray, 1840 (77)
- Family Pleiodontidae Rochebrune, 1904 accepted as Iridinidae Swainson, 1840
- Family Pseudomulleriidae Starobogatov, 1970 accepted as Etheriidae Deshayes, 1832
- Superfamily Hyrioidea Swainson, 1840 accepted as Unionoidea Rafinesque, 1820
- Superfamily Silesunionoidea Skawina & Dzik, 2011 † (11)
- Superfamily Tamesnelloidea Van Damme & Bogan, 2015 † (2)
- Superfamily Unionoidea Rafinesque, 1820 (2 417)
- Family Deccanoidea N. H. Shah & Patel, 2024 † accepted as Deccanoidoidea N. H. Shah & Patel, 2024 †
- Family Pachycardiidae L. R. Cox, 1961 † accepted as Trigonodidae Modell, 1942 †
- Family Silesunionina Skawina & Dzik, 2011 † accepted as Silesunionoidea Skawina & Dzik, 2011 †
- Genus Araripenaia V. R. Silva et al., 2020 † (1)
- Family Lyrodesmatidae P. Fischer, 1886 † (8)
- Family Pseudarcidae Scarlato & Starobogatov, 1979 † (3)
- Family Thoraliidae N. J. Morris, 1980 †
- Superorder Heteroconchia incertae sedis † (1)
- Infraclass Pteriomorphia (6 658)
- Subclass Bivalvia incertae sedis (7)
- Subclass Palaeotaxodonta accepted as Nuculida
- Subclass Paleoheterodonta accepted as Palaeoheterodonta
- Subclass Protobranchia (1 365)
- Infraclass Cryptodonta † (342)
- Class Caudofoveata (143)
- Class Cephalopoda (1 834)
- Class Conchifera accepted as Bivalvia
- Class Cricoconarida † (1)
- Class Gastropoda (102 697)
- Class Lamellibranchiata accepted as Bivalvia
- Class Loricata accepted as Polyplacophora
- Class Mollusca incertae sedis † (372)
- Class Monoplacophora (229)
- Class Pelecypoda accepted as Bivalvia
- Class Polyplacophora (1 377)
- Class Polyplaxiphora accepted as Polyplacophora
- Class Rostroconchia † (64)
- Class Scaphopoda (752)
- Class Solenoconchia accepted as Scaphopoda
- Class Solenogastres (313)
- Subclass Chaetodermomorpha accepted as Caudofoveata