1. Subfamily Echinichinae F. G. Thompson & Naranjo-García, 2012
   1. Genus Echinix F. G. Thompson & Naranjo-García, 2012
2. Subfamily Helminthoglyptinae Pilsbry, 1939
   1. Genus Glypterpes Pilsbry, 1893 †
   2. Tribe Helminthoglyptini Pilsbry, 1939
      1. Genus Cahuillus B. Roth, 1996
      2. Genus Chamaearionta S. S. Berry, 1930
      3. Genus Eremarionta Pilsbry, 1913
      4. Genus Greggelix W. B. Miller, 1972
      5. Genus Helminthoglypta Ancey, 1887
      6. Genus Herpeteros S. S. Berry, 1947
      7. Genus Martirelix W. B. Miller, 1982
      8. Genus Micrarionta Ancey, 1880
      9. Genus Noyo B. Roth, 1996
      10. Genus Rothelix W. B. Miller, 1985
      11. Genus Sonorelix S. S. Berry, 1943
      12. Genus Xerarionta Pilsbry, 1913
      13. Genus Eremariontoides W. B. Miller, 1981 accepted as Eremarionta Pilsbry, 1913 (unaccepted > junior subjective synonym)
      14. Genus Plesarionta Pilsbry, 1939 accepted as Xerarionta (Plesarionta) Pilsbry, 1939 represented as Xerarionta Pilsbry, 1913
   3. Genus Mesoglypterpes Yen, 1952 †
   4. Tribe Sonorellini Pilsbry, 1939
      1. Genus Maricopella B. Roth, 1996
      2. Genus Mohavelix S. S. Berry, 1943
      3. Genus Myotophallus Pilsbry, 1939
      4. Genus Sonorella Pilsbry, 1900
      5. Genus Masculus Pilsbry, 1939 accepted as Sonorella Pilsbry, 1900 (unaccepted > junior subjective synonym)
      6. Genus Sonoranax Pilsbry, 1939 accepted as Sonorella Pilsbry, 1900 (unaccepted > junior subjective synonym)
   5. Genus Pseudolisinoe Wenz, 1923 † accepted as Glypterpes Pilsbry, 1893 † (unaccepted > junior objective synonym)
   6. Tribe Sonorelicini B. Roth, 1996 accepted as Helminthoglyptini Pilsbry, 1939
3. Subfamily Humboldtianinae Pilsbry, 1939
   1. Tribe Bunnyini H. Nordsieck, 1987
      1. Genus Bunnya H. B. Baker, 1942
   2. Tribe Humboldtianini Pilsbry, 1939
      1. Genus Humboldtiana Ihering, 1892
   3. Genus Skinnerelix Evanoff & B. Roth, 1992 †
4. Subfamily Lysinoinae Hoffmann, 1928
   1. Tribe Leptariontini H. Nordsieck, 1987
      1. Genus Leptarionta Crosse & P. Fischer, 1872
      2. Genus Semiconchula Naranjo-García & Polaco, 2000
      3. Genus Tryonigens Pilsbry, 1927
   2. Tribe Lysinoini Hoffmann, 1928
      1. Genus Lysinoe H. Adams & A. Adams, 1855
   3. Tribe Metostracini H. Nordsieck, 1987
      1. Genus Cryptostrakon W. G. Binney, 1879
      2. Genus Metostracon Pilsbry, 1900
      3. Genus Cryptostracon [sic] accepted as Cryptostrakon W. G. Binney, 1879 (unaccepted > misspelling - incorrect subsequent spelling)
   4. Genus Aglaja Albers, 1850 accepted as Lysinoe H. Adams & A. Adams, 1855 (Invalid: junior homonym of Aglaja Renier, 1807 [Opisthobranchia]; Lysinoe is a replacement name)
   5. Genus Odontura Crosse & P. Fischer, 1872 accepted as Lysinoe H. Adams & A. Adams, 1855 (unaccepted > junior objective synonym)
5. Subfamily Monadeniinae H. Nordsieck, 1987
   1. Genus Monadenia Pilsbry, 1895
6. Subfamily Xanthonychinae Strebel & Pfeffer, 1880
   1. Genus Xanthonyx Crosse & P. Fischer, 1867
7. Subfamily Epiphragmophorinae Hoffmann, 1928 accepted as Epiphragmophoridae Hoffmann, 1928 (original rank)
8. Subfamily Metostracinae H. Nordsieck, 1987 accepted as Metostracini H. Nordsieck, 1987 (original rank)

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